Identification Of Drug Related Problems (DRPS) And The Rationality Of The Use Of Antidiabetic In Patients With Type 2 Outpatient Diabetes Mellitus At Dr.Rm. Djoelham Binjai

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Identification of Drug-Related Problems (DRPS) and the Rationality of the Use of Antidiabetic in Patients with Type 2 Outpatient Diabetes Mellitus at Dr. R.M. Djoelham Binjai

Introduction

Diabetes mellitus is a metabolic disease characterized by hyperglycemia, which occurs due to disorders of insulin secretion, insulin action, or both. According to basic health research in 2018, the prevalence of diabetes mellitus in Indonesia reached 2%. The occurrence of problems related to drug use (drug-related problem/DRPS) can prevent or slow down the patient in achieving the desired therapy. The use of irrational drugs can cause therapy to be less effective and efficient. Therefore, it is essential to identify the incidence of DRPS and assess the rationality of the use of antidiabetic in patients with type 2 diabetes mellitus undergoing treatment at Dr. R.M. Djoelham Binjai.

Background of the Study

Diabetes mellitus is a chronic disease that requires long-term management. The management of diabetes involves the use of antidiabetic medications, lifestyle modifications, and regular monitoring of blood glucose levels. However, the use of antidiabetic medications can be associated with various drug-related problems, including drug interactions, adverse reactions, and inappropriate use. These problems can lead to suboptimal control of blood glucose levels, increased risk of complications, and reduced quality of life.

Research Purposes

The primary purpose of this study is to identify the incidence of DRPS and assess the rationality of the use of antidiabetic in patients with type 2 diabetes mellitus undergoing treatment at Dr. R.M. Djoelham Binjai. The study aims to investigate the prevalence of DRPS, the types of DRPS, and the rationality of the use of antidiabetic medications in patients with type 2 diabetes mellitus.

Research Methods

This study employed a non-experimental observational study with a retrospective longitudinal design. The sample consisted of medical record data of outpatients who met the inclusion criteria at Dr. R.M. Djoelham Binjai in the period of January-December 2021. The inclusion criteria were patients with type 2 diabetes mellitus who were receiving antidiabetic medications. The exclusion criteria were patients who were receiving other types of medications that could interact with antidiabetic medications.

The identification of DRPS was carried out referring to the guidelines of Cipolle et al., 1998. The rationality of drug use was evaluated based on the 2017 Ministry of Health guidelines. The data were collected from the medical records of the patients and analyzed using descriptive statistics.

Research Results

The results of this study indicate the incidence of DRPS. Of the 102 patients who meet the inclusion criteria, 34 cases of DRPS were identified among 34 patients with type 2 diabetes mellitus. The most common problem was drug interaction, with 30 cases (88.24%). There were 3 cases (8.82%) that required additional therapy, and 1 case (2.94%) was identified as inappropriate drug use.

The level of rationality of the use of antidiabetic based on the right criteria for patients was 99.01%, with a correct indication reaching 100%, the appropriate type of drug was 76.67%, and the right dose also reached 100%.

Discussion

The results of this study indicate that there is an incidence of DRPS in patients with type 2 diabetes mellitus in Dr. R.M. Djoelham Binjai in the January-December 2021 period. Although there is a high level of rationality for several criteria, the use of antidiabetic as a whole still shows irregularity. This shows the need for further attention in managing diabetes therapy to prevent problems that can interfere with the effectiveness of treatment.

The most common problem identified in this study was drug interaction. This is consistent with previous studies that have reported drug interactions as a common cause of DRPS. The use of antidiabetic medications can be associated with various drug interactions, including interactions with other medications, food, and herbal supplements.

The level of rationality of the use of antidiabetic based on the right criteria for patients was high, with a correct indication reaching 100%. However, the appropriate type of drug was only 76.67%, and the right dose also reached 100%. This suggests that there may be some irregularity in the use of antidiabetic medications, which can lead to suboptimal control of blood glucose levels and increased risk of complications.

Conclusion

In conclusion, this study found that there is an incidence of DRPS in patients with type 2 diabetes mellitus in Dr. R.M. Djoelham Binjai in the January-December 2021 period. Although there is a high level of rationality for several criteria, the use of antidiabetic as a whole still shows irregularity. This shows the need for further attention in managing diabetes therapy to prevent problems that can interfere with the effectiveness of treatment.

Further research needs to be done to identify the factors that cause this irregularity and improvement efforts that can be made to improve the quality of therapy in diabetes patients. With better knowledge of DRPS and the rationality of drug use, it is expected to increase the results of type 2 diabetes mellitus treatment and the quality of life of patients in Indonesia.

Recommendations

Based on the findings of this study, the following recommendations are made:

  1. Regular monitoring of blood glucose levels: Regular monitoring of blood glucose levels is essential to prevent problems that can interfere with the effectiveness of treatment.
  2. Improvement of diabetes education: Diabetes education is essential to improve the knowledge and skills of patients with type 2 diabetes mellitus.
  3. Optimization of antidiabetic therapy: Optimization of antidiabetic therapy is essential to improve the control of blood glucose levels and reduce the risk of complications.
  4. Identification of DRPS: Identification of DRPS is essential to prevent problems that can interfere with the effectiveness of treatment.
  5. Improvement of the quality of therapy: Improvement of the quality of therapy is essential to improve the control of blood glucose levels and reduce the risk of complications.

Limitations of the Study

This study has several limitations. The sample size was small, and the study was conducted in a single hospital. The study only included patients with type 2 diabetes mellitus who were receiving antidiabetic medications. The study did not include patients who were receiving other types of medications that could interact with antidiabetic medications.

Future Research Directions

Future research should focus on identifying the factors that cause irregularity in the use of antidiabetic medications and improvement efforts that can be made to improve the quality of therapy in diabetes patients. Future research should also focus on developing strategies to improve the control of blood glucose levels and reduce the risk of complications in patients with type 2 diabetes mellitus.

Conclusion

In conclusion, this study found that there is an incidence of DRPS in patients with type 2 diabetes mellitus in Dr. R.M. Djoelham Binjai in the January-December 2021 period. Although there is a high level of rationality for several criteria, the use of antidiabetic as a whole still shows irregularity. This shows the need for further attention in managing diabetes therapy to prevent problems that can interfere with the effectiveness of treatment. Further research needs to be done to identify the factors that cause this irregularity and improvement efforts that can be made to improve the quality of therapy in diabetes patients.
Q&A: Identification of Drug-Related Problems (DRPS) and the Rationality of the Use of Antidiabetic in Patients with Type 2 Outpatient Diabetes Mellitus at Dr. R.M. Djoelham Binjai

Q: What is the purpose of this study?

A: The primary purpose of this study is to identify the incidence of DRPS and assess the rationality of the use of antidiabetic in patients with type 2 diabetes mellitus undergoing treatment at Dr. R.M. Djoelham Binjai.

Q: What is DRPS?

A: DRPS stands for Drug-Related Problems. It refers to any event or circumstance involving a drug, which results in one or more of the following: harm to the patient, interactions with other drugs, or other problems that may affect the patient's health.

Q: What are the common types of DRPS?

A: The most common types of DRPS identified in this study were drug interactions, which accounted for 88.24% of the cases. Other types of DRPS included additional therapy required (8.82%) and inappropriate drug use (2.94%).

Q: What is the level of rationality of the use of antidiabetic in patients with type 2 diabetes mellitus?

A: The level of rationality of the use of antidiabetic based on the right criteria for patients was 99.01%, with a correct indication reaching 100%, the appropriate type of drug was 76.67%, and the right dose also reached 100%.

Q: What are the implications of this study?

A: The findings of this study suggest that there is an incidence of DRPS in patients with type 2 diabetes mellitus in Dr. R.M. Djoelham Binjai in the January-December 2021 period. Although there is a high level of rationality for several criteria, the use of antidiabetic as a whole still shows irregularity. This shows the need for further attention in managing diabetes therapy to prevent problems that can interfere with the effectiveness of treatment.

Q: What are the recommendations of this study?

A: Based on the findings of this study, the following recommendations are made:

  1. Regular monitoring of blood glucose levels: Regular monitoring of blood glucose levels is essential to prevent problems that can interfere with the effectiveness of treatment.
  2. Improvement of diabetes education: Diabetes education is essential to improve the knowledge and skills of patients with type 2 diabetes mellitus.
  3. Optimization of antidiabetic therapy: Optimization of antidiabetic therapy is essential to improve the control of blood glucose levels and reduce the risk of complications.
  4. Identification of DRPS: Identification of DRPS is essential to prevent problems that can interfere with the effectiveness of treatment.
  5. Improvement of the quality of therapy: Improvement of the quality of therapy is essential to improve the control of blood glucose levels and reduce the risk of complications.

Q: What are the limitations of this study?

A: This study has several limitations. The sample size was small, and the study was conducted in a single hospital. The study only included patients with type 2 diabetes mellitus who were receiving antidiabetic medications. The study did not include patients who were receiving other types of medications that could interact with antidiabetic medications.

Q: What are the future research directions?

A: Future research should focus on identifying the factors that cause irregularity in the use of antidiabetic medications and improvement efforts that can be made to improve the quality of therapy in diabetes patients. Future research should also focus on developing strategies to improve the control of blood glucose levels and reduce the risk of complications in patients with type 2 diabetes mellitus.

Q: What are the implications for clinical practice?

A: The findings of this study have implications for clinical practice. Healthcare providers should be aware of the potential for DRPS and take steps to prevent them. This includes regular monitoring of blood glucose levels, improvement of diabetes education, optimization of antidiabetic therapy, identification of DRPS, and improvement of the quality of therapy.

Q: What are the implications for policy and practice?

A: The findings of this study have implications for policy and practice. Healthcare policymakers should consider the need for regular monitoring of blood glucose levels, improvement of diabetes education, optimization of antidiabetic therapy, identification of DRPS, and improvement of the quality of therapy. This includes developing policies and guidelines to support these efforts.

Q: What are the implications for future research?

A: The findings of this study have implications for future research. Future research should focus on identifying the factors that cause irregularity in the use of antidiabetic medications and improvement efforts that can be made to improve the quality of therapy in diabetes patients. Future research should also focus on developing strategies to improve the control of blood glucose levels and reduce the risk of complications in patients with type 2 diabetes mellitus.